Sickle cell anemia is an inherited disorder. In Africa, a hundred people is affected by this disease. Approximately 8% of people carry the gene have no significant symptoms.
Normally, red blood cells are flexible and round. During a crisis of sickle cell anemia, some red blood cells become stiff and assume a crescent shape. Obstructions occur, leaving the oxygen in the small vessels. The seizure duration is a few minutes to several days.
The lack of oxygen causes pain among other body, back and joints. Painful swelling can occur in the feet and hands. The patient becomes more vulnerable to infections.
Red blood cells die too quickly (10 days instead of 120 days). Unable to be replaced in sufficient quantity, the symptoms of anemia appear (fatigue, shortness of breath).
Much pain caused by narrowed blood vessels or significant shortness of breath due to the significant drop in the number of red blood cells require urgent care.
Medications are prescribed to reduce pain during crises. An iron supplement taken daily may be necessary. Infections are treated with antibiotics. Blood transfusions can sometimes fight anemia.
The altitude (mountain air), physical exertion, stress and cooling are among the factors that could trigger a crisis.
22 avril 2010
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